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Hypoxia Promotes an Adrenergic to Mesenchymal Transcriptional Program Transition in Neuroblastoma

ABSTRACT Adrenergic (ADRN) neuroblastoma cells have a paradoxical increase in TET1 expression and 5‐hydroxymethylcytosine (5‐hmC) deposition in hypoxia. However, the effect of hypoxia on the mesenchymal (MES) lineage remains less well understood. To identify lineage specific hypoxia responses, we ev...

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Xehetasun bibliografikoak
Egile Nagusiak: Gepoliano S. Chaves, Mohansrinivas Chennakesavalu, Kelley Moore, Hannah Adams, Cara Chittenden, Emma Wilkinson, Omar Vayani, Maria E. Kaufman, Alexandre Chlenski, Chuan He, Susan L. Cohn, Mark A. Applebaum
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley 2026-03-01
Saila:Clinical and Translational Science
Sarrera elektronikoa:https://doi.org/10.1111/cts.70508
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