Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis

<p>Abstract</p> <p>Background</p> <p>Granulocyte colony stimulating factor (GCSF) is protective in animal models of various neurodegenerative diseases. We investigated whether pegfilgrastim, GCSF with sustained action, is protective in a mouse model of amyotrophic lateral sclerosis (ALS). ALS is a f...

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Detalhes bibliográficos

Principais autores:	Giniatullina Raisa, Goldsteins Gundars, Ahtoniemi Toni, Wojciechowski Sara, Malm Tarja, Kanninen Katja, Jaronen Merja, Savchenko Ekaterina, Pollari Eveliina, Giniatullin Rashid, Koistinaho Jari, Magga Johanna
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2011-06-01
coleção:	Journal of Neuroinflammation
Assuntos:	Amyotrophic lateral sclerosis GCSF pegfilgrastim inflammation monocytes cytokines
Acesso em linha:	http://www.jneuroinflammation.com/content/8/1/74
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