Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding
Mutations in superoxide dismutase 1 (SOD1) cause paralysis in familial amyotrophic lateral sclerosis and promote its misfolding into neurotoxic aggregates. Previous studies have shown that mice expressing the ALS-causing G85R variant of SOD1 develop paralysis much faster after intraspinal injection...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis Group
2026-12-01
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| Saila: | Prion |
| Gaiak: | |
| Sarrera elektronikoa: | https://www.tandfonline.com/doi/10.1080/19336896.2026.2630484 |
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