Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding
Mutations in superoxide dismutase 1 (SOD1) cause paralysis in familial amyotrophic lateral sclerosis and promote its misfolding into neurotoxic aggregates. Previous studies have shown that mice expressing the ALS-causing G85R variant of SOD1 develop paralysis much faster after intraspinal injection...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2026-12-01
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| coleção: | Prion |
| Assuntos: | |
| Acesso em linha: | https://www.tandfonline.com/doi/10.1080/19336896.2026.2630484 |
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