Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis
Abstract The use of immunotherapy has achieved great advances in the treatment of cancer. Macrophages play a pivotal role in the immune defense system, serving both as phagocytes (removal of pathogens and cancer cells) and as antigen‐presenting cells (activation of T cells). However, research regard...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2019-08-01
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| coleção: | Cancer Medicine |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/cam4.2332 |
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