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A Novel Anti-CD47 Nanobody Tetramer for Cancer Therapy

CD47 acts as a defense mechanism for tumor cells by sending a “don’t eat me” signal via its bond with SIRPα. With CD47’s overexpression linked to poor cancer outcomes, its pathway has become a target in cancer immunotherapy. Though monoclonal antibodies offer specificity, they have limitations like...

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Bibliografische Detailangaben
Hauptverfasser: Nataliya M. Ratnikova, Yulia Kravchenko, Anna Ivanova, Vladislav Zhuchkov, Elena Frolova, Stepan Chumakov
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-01-01
Schriftenreihe:Antibodies
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Online-Zugang:https://www.mdpi.com/2073-4468/13/1/2
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