Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds

The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, survival, proliferation and angiogenesis. Moreover, FAK can be activated by autophosphorylation at p...

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Bibliographic Details

Main Authors:	Nausika Betriu, Anna Andreeva, Anna Alonso, Carlos E. Semino
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2022-07-01
Series:	Biomedicines
Subjects:	stiffness biomechanics FAK self-assembling peptides RAD16-I pancreatic ductal adenocarcinoma
Online Access:	https://www.mdpi.com/2227-9059/10/8/1835
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