Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds

The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, survival, proliferation and angiogenesis. Moreover, FAK can be activated by autophosphorylation at p...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Nausika Betriu, Anna Andreeva, Anna Alonso, Carlos E. Semino
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2022-07-01
Цуврал:	Biomedicines
Нөхцлүүд:	stiffness biomechanics FAK self-assembling peptides RAD16-I pancreatic ductal adenocarcinoma
Онлайн хандалт:	https://www.mdpi.com/2227-9059/10/8/1835
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!