Single-cell and spatial transcriptomic insights into glioma cellular heterogeneity and metabolic adaptations

Glioblastoma, one of the most aggressive and heterogeneous malignant tumors, presents significant challenges for clinical management due to its cellular and metabolic complexity. This review integrates recent advancements in single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics to eluci...

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Principais autores:	Yixin Fu, Yong Yi, Yongxiang Shao, Jingcheng Jiang, Qingshan Deng
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-04-01
Serija:	Frontiers in Immunology
Teme:	glioma tumor microenvironment single-cell tumor-associated macrophages metabolic reprogramming
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1561388/full
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