Doublecortin mutation leads to persistent defects in the Golgi apparatus and mitochondria in adult hippocampal pyramidal cells

Human doublecortin (DCX) mutations are associated with severe brain malformations leading to aberrant neuron positioning (heterotopia), intellectual disability and epilepsy. DCX is a microtubule-associated protein which plays a key role during neurodevelopment in neuronal migration and differentiati...

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Bibliografische Detailangaben

Hauptverfasser:	M.A. Stouffer, R. Khalaf-Nazzal, C. Cifuentes-Diaz, G. Albertini, E. Bandet, G. Grannec, V. Lavilla, J.-F. Deleuze, R. Olaso, M. Nosten-Bertrand, F. Francis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-06-01
Schriftenreihe:	Neurobiology of Disease
Schlagworte:	Cortical malformation Neurodevelopmental disorder Mouse knockout hippocampus Molecular and cellular analysis Morphology
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0969996122000948
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