UBIAD1 alleviates ferroptotic neuronal death by enhancing antioxidative capacity by cooperatively restoring impaired mitochondria and Golgi apparatus upon cerebral ischemic/reperfusion insult

Abstract Background Neuronal death due to over-oxidative stress responses defines the pathology of cerebral ischemic/reperfusion (I/R) insult. Ferroptosis is a form of oxidative cell death that is induced by disruption of the balance between antioxidants and pro-oxidants in cells. However, the poten...

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Detalhes bibliográficos

Principais autores:	Yan Huang, Jianyang Liu, Jialin He, Zhiping Hu, Fengbo Tan, Xuelin Zhu, Fulai Yuan, Zheng Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-04-01
coleção:	Cell & Bioscience
Assuntos:	UBIAD1 Ferroptotic neuronal death Mitochondria Golgi apparatus Cerebral ischemia/reperfusion
Acesso em linha:	https://doi.org/10.1186/s13578-022-00776-9
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