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A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism

Abstract Background Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, a long non-coding RNA, has been shown to suppress tumor growth through the rescuing of PTEN expres...

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Principais autores: Shunye Su, Leyi Liu, Qingfeng Fu, Minghao Ma, Na Yang, Ting Pan, Shengyong Geng, Xue-Feng Yu, Jianqiang Zhu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-07-01
Series:Journal of Nanobiotechnology
Assuntos:
Black phosphorus nanosheets
RNA delivery
ceRNA mechanism
PTEN
Prostate cancer
Acceso en liña:https://doi.org/10.1186/s12951-024-02659-2
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