Multiomics and machine learning-based analysis of pancancer pseudouridine modifications

Abstract Pseudouridine widely affects the stability and function of RNA. However, our knowledge of pseudouridine properties in tumors is incomplete. We systematically analyzed pseudouridine synthases (PUSs) expression, genomic aberrations, and prognostic features in 10907 samples from 33 tumors. We...

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Dades bibliogràfiques

Autors principals:	Jiheng Zhang, Lei Xu, Xiuwei Yan, Jiahe Hu, Xin Gao, Hongtao Zhao, Mo Geng, Nan Wang, Shaoshan Hu
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2024-08-01
Col·lecció:	Discover Oncology
Matèries:	Pseudouridine modification Pancancer Tumor microenvironment Machine learning Antitumor therapy
Accés en línia:	https://doi.org/10.1007/s12672-024-01093-y
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