Multiomics and machine learning-based analysis of pancancer pseudouridine modifications

Abstract Pseudouridine widely affects the stability and function of RNA. However, our knowledge of pseudouridine properties in tumors is incomplete. We systematically analyzed pseudouridine synthases (PUSs) expression, genomic aberrations, and prognostic features in 10907 samples from 33 tumors. We...

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Detalles Bibliográficos

Principais autores:	Jiheng Zhang, Lei Xu, Xiuwei Yan, Jiahe Hu, Xin Gao, Hongtao Zhao, Mo Geng, Nan Wang, Shaoshan Hu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer 2024-08-01
Series:	Discover Oncology
Assuntos:	Pseudouridine modification Pancancer Tumor microenvironment Machine learning Antitumor therapy
Acceso en liña:	https://doi.org/10.1007/s12672-024-01093-y
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