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Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells.

Dramatic changes in gene expression occur in response to extracellular stimuli and during differentiation. Although transcriptional effects are important, alterations in mRNA decay also play a major role in achieving rapid and massive changes in mRNA abundance. Moreover, just as transcription factor...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jerome E Lee, Ju Youn Lee, Jeffrey Wilusz, Bin Tian, Carol J Wilusz
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2010-06-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC2888570?pdf=render
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