Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11

IntroductionBryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. In HIV research, it has shown anti-HIV effects during acute infection and reactivation of latent HIV in chronic infection. As effective CD8+ T cell responses are essential for eliminati...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Ling Li, Manzhi Zhao, Marjan van Meurs, Inge Brouwers-Haspels, Renske J. H. den Dekker, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Shringar Rao, Casper Rokx, Yvonne M. Mueller, Peter D. Katsikis
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2025-01-01
Serier:	Frontiers in Immunology
Fag:	bryostatin-1 exhausted CD8+ T cells HIV MAP kinase 11 IFN-γ production
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1509874/full
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!