Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain
Opioids do not effectively manage pain in many patients with advanced cancer. Because anandamide (AEA) activation of cannabinoid type-1 receptors (CB1R) on nociceptors reduces nociception, manipulation of AEA metabolism in the periphery may be an effective alternative or adjuvant therapy in the mana...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2013-10-01
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| Colección: | Neurobiology of Disease |
| Materias: | |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S0969996113001320 |
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