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The oncogenic circular RNA circ_63706 is a potential therapeutic target in sonic hedgehog-subtype childhood medulloblastomas

Abstract Medulloblastoma (MB) develops through various genetic, epigenetic, and non-coding (nc) RNA-related mechanisms, but the roles played by ncRNAs, particularly circular RNAs (circRNAs), remain poorly defined. CircRNAs are increasingly recognized as stable non-coding RNA therapeutic targets in m...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Keisuke Katsushima, Rudramani Pokhrel, Iqbal Mahmud, Menglang Yuan, Rabi Murad, Prabin Baral, Rui Zhou, Prem Chapagain, Timothy Garrett, Stacie Stapleton, George Jallo, Chetan Bettegowda, Eric Raabe, Robert J. Wechsler-Reya, Charles G. Eberhart, Ranjan J. Perera
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2023-03-01
Rangatū:Acta Neuropathologica Communications
Ngā marau:
Medulloblastoma
Circular RNA
Sonic hedgehog
Global lipidome
Urunga tuihono:https://doi.org/10.1186/s40478-023-01521-0
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