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Host-intrinsic and host-extrinsic factors modulate immunity to Mtb infection, reinfection, and noncanonical vaccination routes

Summary: Tuberculosis (TB) disease states and outcomes are highly heterogeneous. While this makes TB difficult to diagnose, monitor, and treat, it also presents opportunities to identify correlates of protection or disease severity that can be used as biomarkers and help inform future interventions....

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Principais autores: Joshua D. Bromley, Andrew W. Simonson, Alex K. Shalek, JoAnne L. Flynn
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-08-01
Serier:Cell Reports Medicine
Fag:
Mtb reinfection
natural immunity
granuloma
inflammation
homeostasis
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666379125003593
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