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Host-intrinsic and host-extrinsic factors modulate immunity to Mtb infection, reinfection, and noncanonical vaccination routes

Summary: Tuberculosis (TB) disease states and outcomes are highly heterogeneous. While this makes TB difficult to diagnose, monitor, and treat, it also presents opportunities to identify correlates of protection or disease severity that can be used as biomarkers and help inform future interventions....

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Autori principali: Joshua D. Bromley, Andrew W. Simonson, Alex K. Shalek, JoAnne L. Flynn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2025-08-01
Serie:Cell Reports Medicine
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2666379125003593
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