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Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia

A role for enhanced peptidergic transmission, either opioidergic or not, has been proposed for the generation of l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia (LID) on the basis of in situ hybridization studies showing that striatal peptidergic precursor expression consistently correlates...

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Principais autores: Mathieu Bourdenx, Anna Nilsson, Henrik Wadensten, Maria Fälth, Qin Li, Alan R. Crossman, Per E. Andrén, Erwan Bezard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-02-01
coleção:Neurobiology of Disease
Assuntos:
Parkinson's disease
Mass spectrometry
Peptides
l-DOPA-induced dyskinesia
Primate
MPTP
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S096999611300291X
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