Design of a MCoTI-Based Cyclotide with Angiotensin (1-7)-Like Activity
We report for the first time the design and synthesis of a novel cyclotide able to activate the unique receptor of angiotensin (1-7) (AT1-7), the MAS1 receptor. This was accomplished by grafting an AT1-7 peptide analog onto loop 6 of cyclotide MCoTI-I using isopeptide bonds to preserve the α-amino a...
Furkejuvvon:
| Váldodahkkit: | , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
MDPI AG
2016-01-01
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| Ráidu: | Molecules |
| Fáttát: | |
| Liŋkkat: | http://www.mdpi.com/1420-3049/21/2/152 |
| Fáddágilkorat: |
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