Co-Cultured Continuously Bioluminescent Human Cells as Bioreporters for the Detection of Prodrug Therapeutic Impact Pre- and Post-Metabolism

Modern drug discovery workflows require assay systems capable of replicating the complex interactions of multiple tissue types, but that can still function under high throughput conditions. In this work, we evaluate the use of substrate-free autobioluminescence in human cell lines to support the per...

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書誌詳細

主要な著者:	Tingting Xu, Michael Conway, Ashley Frank, Steven Ripp, Gary Sayler, Dan Close
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2017-12-01
シリーズ:	Sensors
主題:	bioluminescence bacterial luciferase pharmaceutical development optical imaging
オンライン･アクセス:	https://www.mdpi.com/1424-8220/17/12/2827
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