Single-Domain Antibodies That Specifically Recognize Intact Capsids of Multiple Foot-and-Mouth Disease Serotype O Strains

Background/Objectives: Intact (146S) foot-and-mouth disease virus (FMDV) particles easily dissociate into 12S particles with a concomitant decreased immunogenicity. Vaccine quality control with 146S-specific single-domain antibodies (VHHs) is hampered by the high strain specificity of most 146S-spec...

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Prif Awduron:	Michiel M. Harmsen, Nishi Gupta, Quillan Dijkstra, Sandra van de Water, Marga van Setten, Aldo Dekker
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2025-05-01
Cyfres:	Vaccines
Pynciau:	foot-and-mouth disease vaccine nanobody single-domain antibody antigenicity
Mynediad Ar-lein:	https://www.mdpi.com/2076-393X/13/5/500
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