Single-Domain Antibodies That Specifically Recognize Intact Capsids of Multiple Foot-and-Mouth Disease Serotype O Strains

Background/Objectives: Intact (146S) foot-and-mouth disease virus (FMDV) particles easily dissociate into 12S particles with a concomitant decreased immunogenicity. Vaccine quality control with 146S-specific single-domain antibodies (VHHs) is hampered by the high strain specificity of most 146S-spec...

Descrición completa

Detalles Bibliográficos

Principais autores:	Michiel M. Harmsen, Nishi Gupta, Quillan Dijkstra, Sandra van de Water, Marga van Setten, Aldo Dekker
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-05-01
Series:	Vaccines
Assuntos:	foot-and-mouth disease vaccine nanobody single-domain antibody antigenicity
Acceso en liña:	https://www.mdpi.com/2076-393X/13/5/500
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!