Dietary salt promotes cognition impairment through GLP-1R/mTOR/p70S6K signaling pathway

Abstract Dietary salt has been associated with cognitive impairment in mice, possibly related to damaged synapses and tau hyperphosphorylation. However, the mechanism underlying how dietary salt causes cognitive dysfunction remains unclear. In our study, either a high-salt (8%) or normal diet (0.5%)...

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Главные авторы:	Xu Yang, Shu Liu, Chuanling Wang, Haixia Fan, Qian Zou, Yingshuang Pu, Zhiyou Cai
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2024-04-01
Серии:	Scientific Reports
Предметы:	Dietary salt High-salt diet (HSD) Normal diet (ND) Cognition impairment Tau hyperphosphorylation
Online-ссылка:	https://doi.org/10.1038/s41598-024-57998-9
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