EZH2 Inhibition by DS3201 Triggers the Kaposi’s Sarcoma-Associated Herpesvirus Lytic Cycle and Potentiates the Effects Induced by SAHA in Primary Effusion Lymphoma Cells

Primary Effusion Lymphoma (PEL) cells carry Kaposi’s sarcoma-associated herpesvirus (KSHV) in a latent state, except for a small number of cells in which the virus replicates to ensure its persistence into the infected host. However, the lytic cycle can be reactivated in vitro by exposing these lymp...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Roberta Gonnella, Flavia Collura, Vincenzo Corrado, Michele Di Crosta, Roberta Santarelli, Mara Cirone
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-09-01
Serija:	Viruses
Teme:	KSHV p53 lytic cycle autophagy PEL cells
Online dostop:	https://www.mdpi.com/1999-4915/16/9/1490
Oznake:	Označite Brez oznak, prvi označite!