Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood–brain barrier model

Abstract Background Human induced pluripotent stem cells (hiPSC) hold great promise for use in cell therapy applications and for improved in vitro models of human disease. So far, most hiPSC differentiation protocols to astroglia use undefined, animal-containing culture matrices. Laminins, which pla...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Louise Delsing, Therése Kallur, Henrik Zetterberg, Ryan Hicks, Jane Synnergren
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2019-08-01
Sarja:	Fluids and Barriers of the CNS
Aiheet:	Astroglia hiPSC In vitro models Differentiation Laminin-521 Blood–brain barrier
Linkit:	http://link.springer.com/article/10.1186/s12987-019-0147-4
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