Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

ABSTRACT Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR. Histo-blood group antigen (HBGA) binding assays serve as a proxy...

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Hlavní autoři:	Matthew D. Moore, Benjamin G. Bobay, Brittany Mertens, Lee-Ann Jaykus
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2016-12-01
Edice:	mSphere
Témata:	aptamer GII.4 histo-blood group antigen infectivity noroviruses
On-line přístup:	https://journals.asm.org/doi/10.1128/mSphere.00298-16
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