LKB1 biology: assessing the therapeutic relevancy of LKB1 inhibitors
Abstract Liver Kinase B1 (LKB1), encoded by Serine-Threonine Kinase 11 (STK11), is a master kinase that regulates cell migration, polarity, proliferation, and metabolism through downstream adenosine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase signalling. Since genetic scree...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2024-06-01
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| Series: | Cell Communication and Signaling |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s12964-024-01689-5 |
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