A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children

Summary: Hispanic/Latino children have the highest risk of acute lymphoblastic leukemia (ALL) in the US compared to other racial/ethnic groups, yet the basis of this remains incompletely understood. Through genetic fine-mapping analyses, we identified a new independent childhood ALL risk signal near...

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Bibliografski detalji

Glavni autori:	Adam J. de Smith, Lara Wahlster, Soyoung Jeon, Linda Kachuri, Susan Black, Jalen Langie, Liam D. Cato, Nathan Nakatsuka, Tsz-Fung Chan, Guangze Xia, Soumyaa Mazumder, Wenjian Yang, Steven Gazal, Celeste Eng, Donglei Hu, Esteban González Burchard, Elad Ziv, Catherine Metayer, Nicholas Mancuso, Jun J. Yang, Xiaomei Ma, Joseph L. Wiemels, Fulong Yu, Charleston W.K. Chiang, Vijay G. Sankaran
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-04-01
Serija:	Cell Genomics
Teme:	acute lymphoblastic leukemia childhood leukemia B-ALL IKZF1 GWAS fine-mapping
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2666979X24000685
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