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Long-Term Treatment With Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Suppresses Diabetic Neuropathy and Cataract Formation in Rats

We investigated the chronic functional and histopathological changes in the sciatic nerve and lens of streptozotocin (STZ)-diabetic rats and evaluated the preventive effects of ranirestat (AS-3201), a potent aldose reductase inhibitor, on these changes. Sorbitol levels in the sciatic nerve and lens,...

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Xehetasun bibliografikoak
Egile Nagusiak: Takafumi Matsumoto, Yoshiyuki Ono, Akemi Kuromiya, Kaoru Toyosawa, Yoshinaka Ueda, Vera Bril
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2008-01-01
Saila:Journal of Pharmacological Sciences
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S1347861319314215
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