The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability

Abstract Background ATP-dependent nucleosome remodeling complexes of the imitation switch (ISWI) family slide and space nucleosomes. The ISWI ATPase subunit forms obligate complexes with accessory subunits whose mechanistic roles remain poorly understood. In baker’s yeast, the Isw2 ATPase subunit as...

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Principais autores:	Ashish Kumar Singh, Sabine Ines Grünert, Lena Pfaller, Felix Mueller-Planitz
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-05-01
Serija:	Epigenetics & Chromatin
Teme:	ISW2 Itc1 WAC domain Nucleosome remodeler Nucleosome positioning and spacing Saccharomyces cerevisiae
Online dostop:	https://doi.org/10.1186/s13072-025-00593-7
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