The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability

Abstract Background ATP-dependent nucleosome remodeling complexes of the imitation switch (ISWI) family slide and space nucleosomes. The ISWI ATPase subunit forms obligate complexes with accessory subunits whose mechanistic roles remain poorly understood. In baker’s yeast, the Isw2 ATPase subunit as...

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Hlavní autoři:	Ashish Kumar Singh, Sabine Ines Grünert, Lena Pfaller, Felix Mueller-Planitz
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	Epigenetics & Chromatin
Témata:	ISW2 Itc1 WAC domain Nucleosome remodeler Nucleosome positioning and spacing Saccharomyces cerevisiae
On-line přístup:	https://doi.org/10.1186/s13072-025-00593-7
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