The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification

Abstract Objective For treatment of medication-related osteonecrosis of the jaw, one proposed approach is the use of a topical agent to block entry of these medications in oral soft tissues. We tested the ability of phosphonoformic acid (PFA), an inhibitor of bisphosphonate entry through certain s...

Ful tanımlama

Detaylı Bibliyografya

Asıl Yazarlar:	Jacob KIRBY, Makayla STANDFEST, Jessica BINKLEY, Charles BARNES, Evan BROWN, Tyler CAIRNCROSS, Alex CARTWRIGHT, Danielle DADISMAN, Colten MOWAT, Daniel WILMOT, Theodore HOUSEMAN, Conner MURPHY, Caleb ENGELSMAN, Josh HALLER, Daniel JONES
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Faculdade De Odontologia De Bauru - USP 2024-09-01
Seri Bilgileri:	Journal of Applied Oral Science
Konular:	Bisphosphonate-associated osteonecrosis of the jaw Dynamins Endosomes Fibroblasts Zoledronic acid
Online Erişim:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100454&lng=en&tlng=en
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!