A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice

As an important secretory organ, skeletal muscle has drawn attention as a potential target tissue for type 2 diabetic mellitus (T2DM). Recent peptidomics approaches have been applied to identify secreted peptides with potential bioactive. However, comprehensive analysis of the secreted peptides from...

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Detalhes bibliográficos

Principais autores:	Yanting Wu, Mei Han, Yan Wang, Yao Gao, Xianwei Cui, Pengfei Xu, Chenbo Ji, Tianying Zhong, Lianghui You, Yu Zeng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-10-01
coleção:	Frontiers in Endocrinology
Assuntos:	mass spectrometry secreted peptide skeletal muscle insulin resistance Irs1-Akt signaling pathway Pgc1α
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fendo.2019.00741/full
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