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In vitro HIV-1 selective integration into the target sequence and decoy-effect of the modified sequence.

Although there have been a few reports that the HIV-1 genome can be selectively integrated into the genomic DNA of cultured host cell, the biochemistry of integration selectivity has not been fully understood. We modified the in vitro integration reaction protocol and developed a reaction system wit...

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Autors principals: Tatsuaki Tsuruyama, Tonau Nakai, Takuya Hiratsuka, Guang Jin, Takuro Nakamura, Kenichi Yoshikawa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC2973958?pdf=render
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