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In vitro HIV-1 selective integration into the target sequence and decoy-effect of the modified sequence.

Although there have been a few reports that the HIV-1 genome can be selectively integrated into the genomic DNA of cultured host cell, the biochemistry of integration selectivity has not been fully understood. We modified the in vitro integration reaction protocol and developed a reaction system wit...

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Auteurs principaux: Tatsuaki Tsuruyama, Tonau Nakai, Takuya Hiratsuka, Guang Jin, Takuro Nakamura, Kenichi Yoshikawa
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2010-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC2973958?pdf=render
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