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Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array

To address the limitations in current classic twin/family research on the genetic and/or environmental causes of human methylomic variation, we measured blood DNA methylation for 479 women (mean age 56 years) including 66 monozygotic (MZ), 66 dizygotic (DZ) twin pairs and 215 sisters of twins, and 1...

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Main Authors: Shuai Li, Ee Ming Wong, Tuong L. Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S. Dite, Graham G. Giles, Richard Saffery, Melissa C. Southey, John L. Hopper
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2017-11-01
Series:Epigenetics
Subjects:
dna methylation
humanmethylation450 array
familial aggregation
twin study
heritability
Online Access:http://dx.doi.org/10.1080/15592294.2017.1384891
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