Synthesis of pyrazole and pyrazoline derivatives of β-ionone: Exploring anti-inflammatory potential, cytotoxicity, and molecular docking insights

In the present paper, pyrazole and pyrazoline derivatives of β-ionone were synthesized. The protocol involved intramolecular oxidative C–H amination of hydrazone to yield corresponding pyrazole in moderate to good yields. Another methodology comprising of condensation of hydrazine hydrochloride with...

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Hlavní autoři:	Monika Sihag, Anju Manuja, Swati Rani, Rinku Soni, Neha Rani, Sandeep Malik, Kirti Bhardwaj, Balvinder Kumar, Mayank Kinger, Monika Miglani, Deepak Kumar Aneja
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-12-01
Edice:	European Journal of Medicinal Chemistry Reports
Témata:	Pyrazole Pyrazoline Hydrazone Inflammation Bovine serum albumin assay Molecular docking
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2772417424000761
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