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The Effect of 1,2,4-Triazole-3-thiol Derivatives Bearing Hydrazone Moiety on Cancer Cell Migration and Growth of Melanoma, Breast, and Pancreatic Cancer Spheroids

4-Phenyl-3-[2-(phenylamino)ethyl]-1<i>H</i>-1,2,4-triazole-5(4<i>H</i>)-thione was used as a starting compound for the synthesis of the corresponding 1,2,4-triazol-3-ylthioacetohydrazide, which reacts with isatins and various aldehydes bearing aromatic and heterocyclic moieties provided target hydra...

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Autori principali: Aida Šermukšnytė, Kristina Kantminienė, Ilona Jonuškienė, Ingrida Tumosienė, Vilma Petrikaitė
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-08-01
Serie:Pharmaceuticals
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Accesso online:https://www.mdpi.com/1424-8247/15/8/1026
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