The Matrix Protein Tropoelastin Prolongs Mesenchymal Stromal Cell Vitality and Delays Senescence During Replicative Aging

Abstract Cellular senescence leads to the functional decline of regenerative cells such as mesenchymal stromal/stem cells (MSCs), which gives rise to chronic conditions and contributes to poor cell therapy outcomes. Aging tissues are associated with extracellular matrix (ECM) dysregulation, includin...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Sunny Shinchen Lee, Aleen Al Halawani, Jonathan D. Teo, Anthony S. Weiss, Giselle C. Yeo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-10-01
Edice:	Advanced Science
Témata:	aging fitness mesenchymal stromal cells senescence stem cells tropoelastin
On-line přístup:	https://doi.org/10.1002/advs.202402168
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!