Organocatalytic cascade aza-Michael/hemiacetal reaction between disubstituted hydrazines and α,β-unsaturated aldehydes: Highly diastereo- and enantioselective synthesis of pyrazolidine derivatives

The catalytic synthesis of nitrogen-containing heterocycles is of great importance to medicinal and synthetic chemists, and also a challenge for modern chemical methodology. In this paper, we report the synthesis of pyrazolidine derivatives through a domino aza-Michael/hemiacetal sequence with chira...

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Bibliografiske detaljer

Principais autores:	Zhi-Cong Geng, Jian Chen, Ning Li, Xiao-Fei Huang, Yong Zhang, Ya-Wen Zhang, Xing-Wang Wang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Beilstein-Institut 2012-10-01
Serier:	Beilstein Journal of Organic Chemistry
Fag:	aza-Michael domino hydrazine organocatalysis pyrazolidine
Online adgang:	https://doi.org/10.3762/bjoc.8.195
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