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Organocatalytic cascade aza-Michael/hemiacetal reaction between disubstituted hydrazines and α,β-unsaturated aldehydes: Highly diastereo- and enantioselective synthesis of pyrazolidine derivatives

The catalytic synthesis of nitrogen-containing heterocycles is of great importance to medicinal and synthetic chemists, and also a challenge for modern chemical methodology. In this paper, we report the synthesis of pyrazolidine derivatives through a domino aza-Michael/hemiacetal sequence with chira...

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Autori principali: Zhi-Cong Geng, Jian Chen, Ning Li, Xiao-Fei Huang, Yong Zhang, Ya-Wen Zhang, Xing-Wang Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2012-10-01
Serie:Beilstein Journal of Organic Chemistry
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Accesso online:https://doi.org/10.3762/bjoc.8.195
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