Mesenchymal stem cell suppresses the efficacy of CAR-T toward killing lymphoma cells by modulating the microenvironment through stanniocalcin-1

Stem cells play critical roles both in the development of cancer and therapy resistance. Although mesenchymal stem cells (MSCs) can actively migrate to tumor sites, their impact on chimeric antigen receptor modified T cell (CAR-T) immunotherapy has been little addressed. Using an in vitro cell co-cu...

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Egile Nagusiak:	Rui Zhang, Qingxi Liu, Sa Zhou, Hongpeng He, Mingfeng Zhao, Wenjian Ma
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	eLife Sciences Publications Ltd 2023-02-01
Saila:	eLife
Gaiak:	mesenchymal stem cells CAR-T stanniocalcin-1 cancer therapy macrophages pfeiffer cells
Sarrera elektronikoa:	https://elifesciences.org/articles/82934
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