A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport.
All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule arrays such as the mitotic spindle. Cargo-specific adaptors engage with dynein to recruit and activate the motor, but the molecular mechanism...
Na minha lista:
| Principais autores: | , , , , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2019-01-01
|
| 叢編: | PLoS Biology |
| 在線閱讀: | https://doi.org/10.1371/journal.pbio.3000100 |
| 標簽: |
沒有標簽, 成為第一個標記此記錄!
|