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The evolutionary entanglement of flipons with zinc fingers and retroelements has engendered a large family of Z-DNA and G-quadruplex binding proteins

Sequences called flipons can adopt discrete, alternative nucleic acid conformations, such as the left-handed Z-DNA and Z-RNA double helices (referred to collectively as ZNA), and the four-stranded RNA and DNA G-quadruplexes. Each flipon conformation encodes different information. For example, the ba...

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Autor principal: Alan Herbert
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2025-10-01
Colección:Open Biology
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Acceso en línea:https://royalsocietypublishing.org/doi/10.1098/rsob.250171
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