The ancient Z-DNA and Z-RNA specific Zα fold has evolved modern roles in immunity and transcription through the natural selection of flipons
The Zα fold specifically binds to both Z-DNA and Z-RNA, left-handed nucleic acid structures that form under physiological conditions and are encoded by flipons. I trace the Zα fold back to unicellular organisms representing all three domains of life and to the realm of giant nucleocytoplasmic DNA vi...
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| Formato: | Artigo |
| Idioma: | Inglês |
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The Royal Society
2024-06-01
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| Series: | Royal Society Open Science |
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| Acceso en liña: | https://royalsocietypublishing.org/doi/10.1098/rsos.240080 |
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