Age/autoimmunity-associated B cells in inflammatory arthritis: An emerging therapeutic target

Age/autoimmunity-associated B cells (ABCs) are a novel B cell subpopulation with a unique transcriptional signature and cell surface phenotype. They are not sensitive to BCR but rely on TLR7 or TLR9 in the context of T cell-derived cytokines for the differentiation. It has been established that aber...

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Hlavní autoři:	Zhen-yu Li, Ming-Long Cai, Yi Qin, Zhu Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-01-01
Edice:	Frontiers in Immunology
Témata:	age-associated B cells inflammatory arthritis autoimmune diseases immunopathogenesis therapeutic target
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1103307/full
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