In vitro study of uptake and synthesis of creatine and its precursors by cerebellar granule cells and astrocytes suggests some hypotheses on the physiopathology of the inherited disorders of creatine metabolism

<p>Abstract</p> <p>Background</p> <p>The discovery of the inherited disorders of creatine (Cr) synthesis and transport in the last few years disclosed the importance of blood Cr supply for the normal functioning of the brain. These putatively rare diseases share a common pathogenetic mechanism (the...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Carducci Claudia, Carducci Carla, Santagata Silvia, Adriano Enrico, Artiola Cristiana, Thellung Stefano, Gatta Elena, Robello Mauro, Florio Tullio, Antonozzi Italo, Leuzzi Vincenzo, Balestrino Maurizio
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2012-04-01
Sarja:	BMC Neuroscience
Aiheet:	L-arginine:glycine amidinotransferase (AGAT) Creatine transporter (CT1) S-adenosylmethionine: guanidinoacetate N-methyltransferase (GAMT) Energetic metabolism in CNS Mass spectrometry Creatine transporter gene (SLC6A8)
Linkit:	http://www.biomedcentral.com/1471-2202/13/41
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